Cargando…
MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs
Chronic liver disease mediated by the activation of hepatic stellate cells (HSCs) leads to liver fibrosis. The signal adaptor MyD88 of Toll-like receptor (TLR) signaling is involved during the progression of liver fibrosis. However, the specific role of MyD88 in myeloid cells in liver fibrosis has n...
Autores principales: | Ge, Shuang, Yang, Wei, Chen, Haiqiang, Yuan, Qi, Liu, Shi, Zhao, Yongxiang, Zhang, Jinhua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622429/ https://www.ncbi.nlm.nih.gov/pubmed/34830293 http://dx.doi.org/10.3390/ijms222212413 |
Ejemplares similares
-
MyD88 in macrophages protects against colitis via inhibiting the activation of NLRP3 inflammasome in epithelial cells
por: Liu, Shi, et al.
Publicado: (2022) -
MyD88 in hepatic stellate cells enhances liver fibrosis via promoting macrophage M1 polarization
por: Zhang, Jie, et al.
Publicado: (2022) -
Atorvastatin suppresses NLRP3 inflammasome activation in intracerebral hemorrhage via TLR4- and MyD88-dependent pathways
por: Chen, Duo, et al.
Publicado: (2022) -
Alternative activation of macrophages by filarial nematodes is MyD88-independent
por: Mylonas, Katie J., et al.
Publicado: (2013) -
Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome
por: Sun, Panpan, et al.
Publicado: (2019)