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The Proteoglycan Biglycan Modulates Platelet Adhesion and Thrombus Formation in a GPVI-Dependent Manner

Background: Vascular injury induces the exposure of subendothelial extracellular matrix (ECM) important to serve as substrate for platelets to adhere to the injured vessel wall to avoid massive blood loss. Different ECM proteins are known to initiate platelet adhesion and activation. In atherosclero...

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Detalles Bibliográficos
Autores principales: Hoermann, Henrike, Krueger, Irena, Maurus, Nadine, Reusswig, Friedrich, Sun, Yi, Kohlmorgen, Christina, Grandoch, Maria, Fischer, Jens W., Elvers, Margitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622445/
https://www.ncbi.nlm.nih.gov/pubmed/34830059
http://dx.doi.org/10.3390/ijms222212168