Thiosemicarbazone Copper Chelator BLT-1 Blocks Apicomplexan Parasite Replication by Selective Inhibition of Scavenger Receptor B Type 1 (SR-BI)

Coccidian parasites are obligate intracellular pathogens that affect humans and animals. Apicomplexans are defective in de novo synthesis of cholesterol, which is required for membrane biosynthesis and offspring formation. In consequence, cholesterol has to be scavenged from host cells. It is mainly...

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Detalles Bibliográficos
Autores principales: Larrazabal, Camilo, López-Osorio, Sara, Velásquez, Zahady D., Hermosilla, Carlos, Taubert, Anja, Silva, Liliana M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622581/
https://www.ncbi.nlm.nih.gov/pubmed/34835496
http://dx.doi.org/10.3390/microorganisms9112372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622581/
https://www.ncbi.nlm.nih.gov/pubmed/34835496
http://dx.doi.org/10.3390/microorganisms9112372

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