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Thiosemicarbazone Copper Chelator BLT-1 Blocks Apicomplexan Parasite Replication by Selective Inhibition of Scavenger Receptor B Type 1 (SR-BI)
Coccidian parasites are obligate intracellular pathogens that affect humans and animals. Apicomplexans are defective in de novo synthesis of cholesterol, which is required for membrane biosynthesis and offspring formation. In consequence, cholesterol has to be scavenged from host cells. It is mainly...
Autores principales: | Larrazabal, Camilo, López-Osorio, Sara, Velásquez, Zahady D., Hermosilla, Carlos, Taubert, Anja, Silva, Liliana M. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622581/ https://www.ncbi.nlm.nih.gov/pubmed/34835496 http://dx.doi.org/10.3390/microorganisms9112372 |
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