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Lipidomics Reveals Cisplatin-Induced Renal Lipid Alterations during Acute Kidney Injury and Their Attenuation by Cilastatin

Nephrotoxicity is a major complication of cisplatin-based chemotherapy, leading to acute kidney injury in ca. 30% of patients, with no preventive intervention or treatment available for clinical use. Cilastatin has proved to exert a nephroprotective effect for cisplatin therapies in in vitro and in...

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Detalles Bibliográficos
Autores principales: Moreno-Gordaliza, Estefanía, Marazuela, Maria Dolores, Pastor, Óscar, Lázaro, Alberto, Gómez-Gómez, María Milagros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622622/
https://www.ncbi.nlm.nih.gov/pubmed/34830406
http://dx.doi.org/10.3390/ijms222212521