Use of Drug Claims Data and a Medication Risk Score to Assess the Impact of CYP2D6 Drug Interactions among Opioid Users on Healthcare Costs

Cytochrome P450 2D6 (CYP2D6) activity is highly variable due to several factors, including genetic polymorphisms and drug-drug-gene interactions. Hydrocodone, oxycodone, codeine, and tramadol the most commonly prescribed CYP2D6-activated opioids for pain. However, the co-administration of CYP2D6 int...

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Detalles Bibliográficos
Autores principales: Michaud, Veronique, Bikmetov, Ravil, Smith, Matt K., Dow, Pamela, Darakjian, Lucy I., Deodhar, Malavika, Cicali, Brian, Bain, Kevin T., Turgeon, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622634/
https://www.ncbi.nlm.nih.gov/pubmed/34834526
http://dx.doi.org/10.3390/jpm11111174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622634/
https://www.ncbi.nlm.nih.gov/pubmed/34834526
http://dx.doi.org/10.3390/jpm11111174

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