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Contribution of Lipid Oxidation and Ferroptosis to Radiotherapy Efficacy

Radiotherapy promotes tumor cell death and senescence through the induction of oxidative damage. Recent work has highlighted the importance of lipid peroxidation for radiotherapy efficacy. Excessive lipid peroxidation can promote ferroptosis, a regulated form of cell death. In this review, we addres...

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Detalles Bibliográficos
Autores principales: Pearson, Ashley N., Carmicheal, Joseph, Jiang, Long, Lei, Yu Leo, Green, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622791/
https://www.ncbi.nlm.nih.gov/pubmed/34830482
http://dx.doi.org/10.3390/ijms222212603