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Evidence That a TRPA1-Mediated Murine Model of Temporomandibular Joint Pain Involves NLRP3 Inflammasome Activation

This study investigates the role of transient receptor potential ankyrin 1 (TRPA1) in murine temporomandibular joint (TMJ) inflammatory hyperalgesia and the influence of the NLR family pyrin domain-containing 3 (NLRP3) inflammasome. Two distinct murine models of TMJ pain and inflammation (zymosan an...

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Detalles Bibliográficos
Autores principales: Kodji, Xenia, Kee, Zizheng, McKenna, Robyn, de Sousa Valente, Joao, Ravenscroft, Harriet, McMillan, Hayley, Gamble, John, Dombrowski, Yvonne, Moynagh, Paul, Brough, David, Lundy, Fionnuala T., Brain, Susan D., El Karim, Ikhlas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622821/
https://www.ncbi.nlm.nih.gov/pubmed/34832855
http://dx.doi.org/10.3390/ph14111073