Design and Development of Autotaxin Inhibitors

Autotaxin (ATX) is the only enzyme of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP2) family with lysophospholipase D (lysoPLD) activity, which is mainly responsible for the hydrolysis of extracellular lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA). LPA can induce vario...

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Detalles Bibliográficos
Autores principales: Jia, Yi, Li, Yan, Xu, Xu-Dong, Tian, Yu, Shang, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622848/
https://www.ncbi.nlm.nih.gov/pubmed/34832985
http://dx.doi.org/10.3390/ph14111203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622848/
https://www.ncbi.nlm.nih.gov/pubmed/34832985
http://dx.doi.org/10.3390/ph14111203

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