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Zinc Induced Aβ(16) Aggregation Modeled by Molecular Dynamics

It is widely accepted that the addition of zinc leads to the formation of neurotoxic nonfibrillar aggregates of beta-amyloid peptides Aβ(40) and Aβ(42) and at the same time destabilizes amyloid fibrils. However, the mechanism of the effect of zinc on beta-amyloid is not fully understood. In this stu...

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Detalles Bibliográficos
Autores principales: Tolstova, Anna P., Makarov, Alexander A., Adzhubei, Alexei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622866/
https://www.ncbi.nlm.nih.gov/pubmed/34830056
http://dx.doi.org/10.3390/ijms222212161