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Nanoencapsulation as a General Solution for Lyophilization of Labile Substrates

Protein macromolecules occur naturally at the nanoscale. The use of a dedicated nanoparticle as a lyophilization excipient, however, has not been reported. Because biopolymeric and lipid nanoparticles often denature protein macromolecules and commonly lack the structural rigidity to survive the free...

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Detalles Bibliográficos
Autores principales: Vallerinteavide Mavelli, Girish, Sadeghi, Samira, Vaidya, Siddhesh Sujit, Kong, Shik Nie, Drum, Chester Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622885/
https://www.ncbi.nlm.nih.gov/pubmed/34834205
http://dx.doi.org/10.3390/pharmaceutics13111790