5-epi-Sinuleptolide from Soft Corals of the Genus Sinularia Exerts Cytotoxic Effects on Pancreatic Cancer Cell Lines via the Inhibition of JAK2/STAT3, AKT, and ERK Activity

Pancreatic ductal adenocarcinoma is one of the most lethal malignancies: more than half of patients are diagnosed with a metastatic disease, which is associated with a five-year survival rate of only 3%. 5-epi-Sinuleptolide, a norditerpene isolated from Sinularia sp., has been demonstrated to posses...

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Detalles Bibliográficos
Autores principales: Tsai, Wan-Chi, Wang, Wen-Hung, Huang, Bo-Cian, Huang, Chiung-Yao, Sheu, Jyh-Horng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623039/
https://www.ncbi.nlm.nih.gov/pubmed/34834023
http://dx.doi.org/10.3390/molecules26226932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623039/
https://www.ncbi.nlm.nih.gov/pubmed/34834023
http://dx.doi.org/10.3390/molecules26226932

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