Clinical Safety and Tolerability of A2NTX, a Novel Low-Molecular-Weight Neurotoxin Derived from Botulinum Neurotoxin Subtype A2, in Comparison with Subtype A1 Toxins

All the botulinum type A neurotoxins available for clinical use are of the A1 subtype. We developed a subtype A2 low-molecular-weight (150 kD (kilo Dalton)) neurotoxin (A2NTX) with less spread and faster entry into the motor nerve terminal than A1 in vitro and in vivo. Preliminary clinical studies s...

Descripción completa

Detalles Bibliográficos
Autores principales: Takeuchi, Toshiaki, Okuno, Tsuyoshi, Miyashiro, Ai, Kohda, Tomoko, Miyamoto, Ryosuke, Izumi, Yuishin, Kozaki, Shunji, Kaji, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623066/
https://www.ncbi.nlm.nih.gov/pubmed/34822610
http://dx.doi.org/10.3390/toxins13110824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623066/
https://www.ncbi.nlm.nih.gov/pubmed/34822610
http://dx.doi.org/10.3390/toxins13110824

Ejemplares similares