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Pharmacological and Epigenetic Regulators of NLRP3 Inflammasome Activation in Alzheimer’s Disease

Activation of the NLRP3 inflammasome complex results in the production of IL-18, Caspase-1 and IL-1β. These cytokines have a beneficial role in promoting inflammation, but an excessive activation of the inflammasome and the consequent constitutive inflammatory status is a negative factor in human pa...

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Detalles Bibliográficos
Autores principales: La Rosa, Francesca, Mancuso, Roberta, Agostini, Simone, Piancone, Federica, Marventano, Ivana, Saresella, Marina, Hernis, Ambra, Fenoglio, Chiara, Galimberti, Daniela, Scarpini, Elio, Clerici, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623160/
https://www.ncbi.nlm.nih.gov/pubmed/34832969
http://dx.doi.org/10.3390/ph14111187