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Pharmacological and Epigenetic Regulators of NLRP3 Inflammasome Activation in Alzheimer’s Disease
Activation of the NLRP3 inflammasome complex results in the production of IL-18, Caspase-1 and IL-1β. These cytokines have a beneficial role in promoting inflammation, but an excessive activation of the inflammasome and the consequent constitutive inflammatory status is a negative factor in human pa...
Autores principales: | La Rosa, Francesca, Mancuso, Roberta, Agostini, Simone, Piancone, Federica, Marventano, Ivana, Saresella, Marina, Hernis, Ambra, Fenoglio, Chiara, Galimberti, Daniela, Scarpini, Elio, Clerici, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623160/ https://www.ncbi.nlm.nih.gov/pubmed/34832969 http://dx.doi.org/10.3390/ph14111187 |
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