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TDP-43 and HERV-K Envelope-Specific Immunogenic Epitopes Are Recognized in ALS Patients

The human endogenous retrovirus-K (HERV-K) and TAR DNA-binding protein 43 (TDP-43) have been associated with the pathophysiology of amyotrophic lateral sclerosis (ALS). Given these findings, we investigated the humoral response against HERV-K envelope surface (env-su) glycoprotein antigens and TDP-4...

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Detalles Bibliográficos
Autores principales: Simula, Elena Rita, Arru, Giannina, Zarbo, Ignazio Roberto, Solla, Paolo, Sechi, Leonardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623164/
https://www.ncbi.nlm.nih.gov/pubmed/34835107
http://dx.doi.org/10.3390/v13112301