Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1A

Here, we report on the synthesis of libraries of new 5-arylidene-2-thioxo-1,3-thiazolidin-4-ones 3 (twenty-two compounds) and new 2-amino-5-arylidene-1,3-thiazol-4(5H)-ones 5 (twenty-four compounds) with stereo controlled Z-geometry under microwave irradiation. The 46 designed final compounds were t...

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Detalles Bibliográficos
Autores principales: Bourahla, Khadidja, Guihéneuf, Solène, Limanton, Emmanuelle, Paquin, Ludovic, Le Guével, Rémy, Charlier, Thierry, Rahmouni, Mustapha, Durieu, Emilie, Lozach, Olivier, Carreaux, François, Meijer, Laurent, Bazureau, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623179/
https://www.ncbi.nlm.nih.gov/pubmed/34832868
http://dx.doi.org/10.3390/ph14111086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623179/
https://www.ncbi.nlm.nih.gov/pubmed/34832868
http://dx.doi.org/10.3390/ph14111086

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