BX795-Organic Acid Coevaporates: Evaluation of Solid-State Characteristics, In Vitro Cytocompatibility and In Vitro Activity against HSV-1 and HSV-2

BX795 is a TANK binding kinase-1 inhibitor that has shown excellent therapeutic activity in murine models of genital and ocular herpes infections on topical delivery. Currently, only the BX795 free base and its hydrochloride salt are available commercially. Here, we evaluate the ability of various o...

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Detalles Bibliográficos
Autores principales: Sutar, Yogesh, Yadavalli, Tejabhiram, Paul, Sagar Kumar, Mallick, Sudipta, Koganti, Raghuram, Chauhan, Harsh, Date, Abhijit A., Shukla, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623185/
https://www.ncbi.nlm.nih.gov/pubmed/34834335
http://dx.doi.org/10.3390/pharmaceutics13111920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623185/
https://www.ncbi.nlm.nih.gov/pubmed/34834335
http://dx.doi.org/10.3390/pharmaceutics13111920

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