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Doxorubicin-Resistant TNBC Cells Exhibit Rapid Growth with Cancer Stem Cell-like Properties and EMT Phenotype, Which Can Be Transferred to Parental Cells through Autocrine Signaling

Emerging evidence suggests that breast cancer stem cells (BCSCs), and epithelial–mesenchymal transition (EMT) may be involved in resistance to doxorubicin. However, it is unlear whether the doxorubicin-induced EMT and expansion of BCSCs is related to cancer dormancy, or outgrowing cancer cells with...

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Detalles Bibliográficos
Autores principales: Paramanantham, Anjugam, Jung, Eun-Joo, Kim, Hye-Jung, Jeong, Bae-Kwon, Jung, Jin-Myung, Kim, Gon-Sup, Chan, Hong-Soon, Lee, Won-Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623267/
https://www.ncbi.nlm.nih.gov/pubmed/34830320
http://dx.doi.org/10.3390/ijms222212438