Novel N7-Arylmethyl Substituted Dinucleotide mRNA 5′ cap Analogs: Synthesis and Evaluation as Modulators of Translation †

Dinucleotide analogs of the messenger RNA cap (m(7)GpppN) are useful research tools and have potential applications as translational inhibitors or reagents for modification of in vitro transcribed mRNAs. It has been previously reported that replacing the methyl group at the N7-position with benzyl (...

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Detalles Bibliográficos
Autores principales: Wojcik, Radoslaw, Baranowski, Marek R., Markiewicz, Lukasz, Kubacka, Dorota, Bednarczyk, Marcelina, Baran, Natalia, Wojtczak, Anna, Sikorski, Pawel J., Zuberek, Joanna, Kowalska, Joanna, Jemielity, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623273/
https://www.ncbi.nlm.nih.gov/pubmed/34834356
http://dx.doi.org/10.3390/pharmaceutics13111941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623273/
https://www.ncbi.nlm.nih.gov/pubmed/34834356
http://dx.doi.org/10.3390/pharmaceutics13111941

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