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Novel N7-Arylmethyl Substituted Dinucleotide mRNA 5′ cap Analogs: Synthesis and Evaluation as Modulators of Translation †
Dinucleotide analogs of the messenger RNA cap (m(7)GpppN) are useful research tools and have potential applications as translational inhibitors or reagents for modification of in vitro transcribed mRNAs. It has been previously reported that replacing the methyl group at the N7-position with benzyl (...
Autores principales: | Wojcik, Radoslaw, Baranowski, Marek R., Markiewicz, Lukasz, Kubacka, Dorota, Bednarczyk, Marcelina, Baran, Natalia, Wojtczak, Anna, Sikorski, Pawel J., Zuberek, Joanna, Kowalska, Joanna, Jemielity, Jacek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623273/ https://www.ncbi.nlm.nih.gov/pubmed/34834356 http://dx.doi.org/10.3390/pharmaceutics13111941 |
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