Co-Evolution of Opioid and Adrenergic Ligands and Receptors: Shared, Complementary Modules Explain Evolution of Functional Interactions and Suggest Novel Engineering Possibilities

Cross-talk between opioid and adrenergic receptors is well-characterized and involves second messenger systems, the formation of receptor heterodimers, and the presence of extracellular allosteric binding regions for the complementary ligand; however, the evolutionary origins of these interactions h...

Descripción completa

Detalles Bibliográficos
Autores principales: Root-Bernstein, Robert, Churchill, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623292/
https://www.ncbi.nlm.nih.gov/pubmed/34833093
http://dx.doi.org/10.3390/life11111217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623292/
https://www.ncbi.nlm.nih.gov/pubmed/34833093
http://dx.doi.org/10.3390/life11111217

Ejemplares similares