Virtual Screening and Molecular Dynamics Simulation Study of Influenza Polymerase PB2 Inhibitors

Influenza A virus is the main cause of worldwide epidemics and annual influenza outbreaks in humans. In this study, a virtual screen was performed to identify compounds that interact with the PB2 cap-binding domain (CBD) of influenza A polymerase. A virtual screening workflow based on Glide docking...

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Detalles Bibliográficos
Autores principales: Zong, Keli, Xu, Lei, Hou, Yuxin, Zhang, Qian, Che, Jinjing, Zhao, Lei, Li, Xingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623395/
https://www.ncbi.nlm.nih.gov/pubmed/34834044
http://dx.doi.org/10.3390/molecules26226944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623395/
https://www.ncbi.nlm.nih.gov/pubmed/34834044
http://dx.doi.org/10.3390/molecules26226944

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