Investigation of the Mechanisms of Cytotoxic Activity of 1,3-Disubstituted Thiourea Derivatives

Substituted thiourea derivatives possess confirmed cytotoxic activity towards cancer but also normal cells. To develop new selective antitumor agents, a series of 3-(trifluoromethyl)phenylthiourea analogs were synthesized, and their cytotoxicity was evaluated in vitro against the cell line panel. Co...

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Detalles Bibliográficos
Autores principales: Strzyga-Łach, Paulina, Chrzanowska, Alicja, Podsadni, Katarzyna, Bielenica, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623398/
https://www.ncbi.nlm.nih.gov/pubmed/34832881
http://dx.doi.org/10.3390/ph14111097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623398/
https://www.ncbi.nlm.nih.gov/pubmed/34832881
http://dx.doi.org/10.3390/ph14111097

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