Novel Multitarget Hydroxamic Acids with a Natural Origin CAP Group against Alzheimer’s Disease: Synthesis, Docking and Biological Evaluation

Hydroxamic acids are one of the most promising and actively studied classes of chemical compounds in medicinal chemistry. In this study, we describe the directed synthesis and effects of HDAC6 inhibitors. Fragments of adamantane and natural terpenes camphane and fenchane, combined with linkers of va...

Descripción completa

Detalles Bibliográficos
Autores principales: Neganova, Margarita, Aleksandrova, Yulia, Suslov, Evgenii, Mozhaitsev, Evgenii, Munkuev, Aldar, Tsypyshev, Dmitry, Chicheva, Maria, Rogachev, Artem, Sukocheva, Olga, Volcho, Konstantin, Klochkov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623418/
https://www.ncbi.nlm.nih.gov/pubmed/34834312
http://dx.doi.org/10.3390/pharmaceutics13111893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623418/
https://www.ncbi.nlm.nih.gov/pubmed/34834312
http://dx.doi.org/10.3390/pharmaceutics13111893

Ejemplares similares