A Rational Design of α-Helix-Shaped Peptides Employing the Hydrogen-Bond Surrogate Approach: A Modulation Strategy for Ras-RasGRF1 Interaction in Neuropsychiatric Disorders

In the last two decades, abnormal Ras (rat sarcoma protein)–ERK (extracellular signal-regulated kinase) signalling in the brain has been involved in a variety of neuropsychiatric disorders, including drug addiction, certain forms of intellectual disability, and autism spectrum disorder. Modulation o...

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Detalles Bibliográficos
Autores principales: Gulotta, Maria Rita, Brambilla, Riccardo, Perricone, Ugo, Brancale, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623491/
https://www.ncbi.nlm.nih.gov/pubmed/34832880
http://dx.doi.org/10.3390/ph14111099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623491/
https://www.ncbi.nlm.nih.gov/pubmed/34832880
http://dx.doi.org/10.3390/ph14111099

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