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Molecular Detection of Borrelia Bacteria in Cerebrospinal Fluid-Optimisation of Pre-Analytical Sample Handling for Increased Analytical Sensitivity

The main tools for clinical diagnostics of Lyme neuroborreliosis (LNB) are based on serology, i.e., detection of antibodies in cerebrospinal fluid (CSF). In some cases, PCR may be used as a supplement, e.g., on CSF from patients with early LNB. Standardisation of the molecular methods and systematic...

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Detalles Bibliográficos
Autores principales: Lager, Malin, Wilhelmsson, Peter, Matussek, Andreas, Lindgren, Per-Eric, Henningsson, Anna J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623531/
https://www.ncbi.nlm.nih.gov/pubmed/34829435
http://dx.doi.org/10.3390/diagnostics11112088