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Ketogal Safety Profile in Human Primary Colonic Epithelial Cells and in Mice

In our previous studies, a ketorolac–galactose conjugate (ketogal) showed prolonged anti-inflammatory and analgesic activity, causing less gastric ulcerogenic effect and renal toxicity than its parent drug ketorolac. In order to demonstrate the safer profile of ketogal compared to ketorolac, histopa...

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Detalles Bibliográficos
Autores principales: Sodano, Federica, Avallone, Bice, Tizzano, Monica, Fogliano, Chiara, Rolando, Barbara, Gazzano, Elena, Riganti, Chiara, Magliocca, Salvatore, Cuozzo, Mariarosaria, Albrizio, Stefania, Calignano, Antonio, Cristiano, Claudia, Russo, Roberto, Rimoli, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623564/
https://www.ncbi.nlm.nih.gov/pubmed/34832931
http://dx.doi.org/10.3390/ph14111149