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Ketogal Safety Profile in Human Primary Colonic Epithelial Cells and in Mice
In our previous studies, a ketorolac–galactose conjugate (ketogal) showed prolonged anti-inflammatory and analgesic activity, causing less gastric ulcerogenic effect and renal toxicity than its parent drug ketorolac. In order to demonstrate the safer profile of ketogal compared to ketorolac, histopa...
Autores principales: | Sodano, Federica, Avallone, Bice, Tizzano, Monica, Fogliano, Chiara, Rolando, Barbara, Gazzano, Elena, Riganti, Chiara, Magliocca, Salvatore, Cuozzo, Mariarosaria, Albrizio, Stefania, Calignano, Antonio, Cristiano, Claudia, Russo, Roberto, Rimoli, Maria Grazia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623564/ https://www.ncbi.nlm.nih.gov/pubmed/34832931 http://dx.doi.org/10.3390/ph14111149 |
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