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Preparation of Cationic Amphiphilic Nanoparticles with Modified Chitosan Derivatives for Doxorubicin Delivery

Polymeric micelle-like nanoparticles have demonstrated effectiveness for the delivery of some poorly soluble or hydrophobic anticancer drugs. In this study, a hydrophobic moiety, deoxycholic acid (DCA) was first bonded on a polysaccharide, chitosan (CS), for the preparation of amphiphilic chitosan (...

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Detalles Bibliográficos
Autores principales: Liu, Xiudong, Zhou, Huofei, Yu, Weiting, Xiong, Xin, Krastev, Rumen, Ma, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623570/
https://www.ncbi.nlm.nih.gov/pubmed/34832408
http://dx.doi.org/10.3390/ma14227010