Transcriptomic Profiling Reveals AKR1C1 and AKR1C3 Mediate Cisplatin Resistance in Signet Ring Cell Gastric Carcinoma via Autophagic Cell Death

Signet ring cell gastric carcinoma (SRCGC) is a lethal malignancy that has developed drug resistance to cisplatin therapies. The aim of this study was to characterize the acquisition of the cisplatin-resistance SRCGC cell line (KATO/DDP cells) and to understand the molecular mechanisms underlying ci...

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Detalles Bibliográficos
Autores principales: Phoo, Nang Lae Lae, Dejkriengkraikul, Pornngarm, Khaw-On, Patompong, Yodkeeree, Supachai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623627/
https://www.ncbi.nlm.nih.gov/pubmed/34830394
http://dx.doi.org/10.3390/ijms222212512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623627/
https://www.ncbi.nlm.nih.gov/pubmed/34830394
http://dx.doi.org/10.3390/ijms222212512

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