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Transcriptomic Profiling Reveals AKR1C1 and AKR1C3 Mediate Cisplatin Resistance in Signet Ring Cell Gastric Carcinoma via Autophagic Cell Death
Signet ring cell gastric carcinoma (SRCGC) is a lethal malignancy that has developed drug resistance to cisplatin therapies. The aim of this study was to characterize the acquisition of the cisplatin-resistance SRCGC cell line (KATO/DDP cells) and to understand the molecular mechanisms underlying ci...
Autores principales: | Phoo, Nang Lae Lae, Dejkriengkraikul, Pornngarm, Khaw-On, Patompong, Yodkeeree, Supachai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623627/ https://www.ncbi.nlm.nih.gov/pubmed/34830394 http://dx.doi.org/10.3390/ijms222212512 |
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