Epigenetics of Myotonic Dystrophies: A Minireview

Myotonic dystrophy type 1 and 2 (DM1 and DM2) are two multisystemic autosomal dominant disorders with clinical and genetic similarities. The prevailing paradigm for DMs is that they are mediated by an in trans toxic RNA mechanism, triggered by untranslated CTG and CCTG repeat expansions in the DMPK...

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Detalles Bibliográficos
Autores principales: Visconti, Virginia Veronica, Centofanti, Federica, Fittipaldi, Simona, Macrì, Elisa, Novelli, Giuseppe, Botta, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623789/
https://www.ncbi.nlm.nih.gov/pubmed/34830473
http://dx.doi.org/10.3390/ijms222212594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623789/
https://www.ncbi.nlm.nih.gov/pubmed/34830473
http://dx.doi.org/10.3390/ijms222212594

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