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Structural Design, Synthesis and Antioxidant, Antileishmania, Anti-Inflammatory and Anticancer Activities of a Novel Quercetin Acetylated Derivative

Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water, extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological use. The aim of this study was to perform structural modification in Q by acetylation, thus, obtaining the quercetin...

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Detalles Bibliográficos
Autores principales: da Silva, Saul Vislei Simões, Barboza, Orlando Maia, Souza, Jéssica Teles, Soares, Érica Novaes, dos Santos, Cleonice Creusa, Pacheco, Luciano Vasconcellos, Santos, Ivanilson Pimenta, Magalhães, Tatiana Barbosa dos Santos, Soares, Milena Botelho Pereira, Guimarães, Elisalva Teixeira, Meira, Cássio Santana, Costa, Silvia Lima, da Silva, Victor Diógenes Amaral, de Santana, Lourenço Luís Botelho, de Freitas Santos Júnior, Aníbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623808/
https://www.ncbi.nlm.nih.gov/pubmed/34834016
http://dx.doi.org/10.3390/molecules26226923