Integrating Elastic Tensor and PC-SAFT Modeling with Systems-Based Pharma 4.0 Simulation, to Predict Process Operations and Product Specifications of Ternary Nanocrystalline Suspensions

Comminution of BCS II APIs below the 1 μm threshold followed by solidification of the obtained nanosuspensions improves their dissolution properties. The breakage process reveals new crystal faces, thus creating altered crystal habits of improved wettability, facilitated by the adsorption of stabili...

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Detalles Bibliográficos
Autores principales: Ouranidis, Andreas, Davidopoulou, Christina, Kachrimanis, Kyriakos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623873/
https://www.ncbi.nlm.nih.gov/pubmed/34834186
http://dx.doi.org/10.3390/pharmaceutics13111771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623873/
https://www.ncbi.nlm.nih.gov/pubmed/34834186
http://dx.doi.org/10.3390/pharmaceutics13111771

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