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Tumor Lymphatic Interactions Induce CXCR2-CXCL5 Axis and Alter Cellular Metabolism and Lymphangiogenic Pathways to Promote Cholangiocarcinoma

Cholangiocarcinoma (CCA), or cancer of bile duct epithelial cells, is a very aggressive malignancy characterized by early lymphangiogenesis in the tumor microenvironment (TME) and lymph node (LN) metastasis which correlate with adverse patient outcome. However, the specific roles of lymphatic endoth...

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Detalles Bibliográficos
Autores principales: Roy, Sukanya, Kumaravel, Subhashree, Banerjee, Priyanka, White, Tori K., O’Brien, April, Seelig, Catherine, Chauhan, Rahul, Ekser, Burcin, Bayless, Kayla J., Alpini, Gianfranco, Glaser, Shannon S., Chakraborty, Sanjukta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623887/
https://www.ncbi.nlm.nih.gov/pubmed/34831316
http://dx.doi.org/10.3390/cells10113093