Retinaldehyde Dehydrogenase Inhibition-Related Adverse Outcome Pathway: Potential Risk of Retinoic Acid Synthesis Inhibition during Embryogenesis

Retinoic acid (RA) is one of the factors crucial for cell growth, differentiation, and embryogenesis; it interacts with the retinoic acid receptor and retinoic acid X receptor to eventually regulate target gene expression in chordates. RA is transformed from retinaldehyde via oxidization by retinald...

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Detalles Bibliográficos
Autores principales: Cho, Kichul, Lee, Sang-Moo, Heo, Jina, Kwon, Yong Min, Chung, Dawoon, Yu, Woon-Jong, Bae, Seung Seob, Choi, Grace, Lee, Dae-Sung, Kim, Youngjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623920/
https://www.ncbi.nlm.nih.gov/pubmed/34822523
http://dx.doi.org/10.3390/toxins13110739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623920/
https://www.ncbi.nlm.nih.gov/pubmed/34822523
http://dx.doi.org/10.3390/toxins13110739

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