Cargando…
Retinaldehyde Dehydrogenase Inhibition-Related Adverse Outcome Pathway: Potential Risk of Retinoic Acid Synthesis Inhibition during Embryogenesis
Retinoic acid (RA) is one of the factors crucial for cell growth, differentiation, and embryogenesis; it interacts with the retinoic acid receptor and retinoic acid X receptor to eventually regulate target gene expression in chordates. RA is transformed from retinaldehyde via oxidization by retinald...
Autores principales: | Cho, Kichul, Lee, Sang-Moo, Heo, Jina, Kwon, Yong Min, Chung, Dawoon, Yu, Woon-Jong, Bae, Seung Seob, Choi, Grace, Lee, Dae-Sung, Kim, Youngjun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623920/ https://www.ncbi.nlm.nih.gov/pubmed/34822523 http://dx.doi.org/10.3390/toxins13110739 |
Ejemplares similares
-
Generation of Retinaldehyde for Retinoic Acid Biosynthesis
por: Belyaeva, Olga V., et al.
Publicado: (2019) -
Inhibition of aldehyde dehydrogenase 1 enhances the cytotoxic effect of retinaldehyde on A549 cancer cells
por: Park, Jin Won, et al.
Publicado: (2017) -
Identification of Active Retinaldehyde Dehydrogenase Isoforms in the Postnatal Human Eye
por: Harper, Angelica R., et al.
Publicado: (2015) -
Development of
a Retinal-Based Probe for the Profiling
of Retinaldehyde Dehydrogenases in Cancer Cells
por: Koenders, Sebastiaan T. A., et al.
Publicado: (2019) -
Deficiency of Retinaldehyde Dehydrogenase 1 Induces BMP2 and Increases Bone Mass In Vivo
por: Nallamshetty, Shriram, et al.
Publicado: (2013)