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The Influence of 5′,8-Cyclo-2′-deoxypurines on the Mitochondrial Repair of Clustered DNA Damage in Xrs5 Cells: The Preliminary Study

The 5′,8-cyclo-2′-deoxypurines (cdPus) affect the DNA structure. When these bulky structures are a part of clustered DNA lesions (CDL), they affect the repair of the other lesions within the cluster. Mitochondria are crucial for cell survival and have their own genome, hence, are highly interesting...

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Detalles Bibliográficos
Autores principales: Boguszewska, Karolina, Kaźmierczak-Barańska, Julia, Karwowski, Bolesław T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623968/
https://www.ncbi.nlm.nih.gov/pubmed/34834133
http://dx.doi.org/10.3390/molecules26227042