Brachytherapy Approach Using (177)Lu Conjugated Gold Nanostars and Evaluation of Biodistribution, Tumor Retention, Dosimetry and Therapeutic Efficacy in Head and Neck Tumor Model

Brachytherapy can provide sufficient doses to head and neck squamous cell carcinoma (HNSCC) with minimal damage to nearby normal tissues. In this study, the β(−)-emitter (177)Lu was conjugated to DTPA-polyethylene glycol (PEG) decorated gold nanostars ((177)Lu-DTPA-pAuNS) used in surface-enhanced Ra...

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Detalles Bibliográficos
Autores principales: Lin, Min-Ying, Hsieh, Hsin-Hua, Chen, Jyh-Cheng, Chen, Chuan-Lin, Sheu, Nin-Chu, Huang, Wen-Sheng, Ho, Shinn-Ying, Chen, Ting-Wen, Lee, Yi-Jang, Wu, Chun-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623985/
https://www.ncbi.nlm.nih.gov/pubmed/34834318
http://dx.doi.org/10.3390/pharmaceutics13111903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623985/
https://www.ncbi.nlm.nih.gov/pubmed/34834318
http://dx.doi.org/10.3390/pharmaceutics13111903

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