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Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGF-β1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial Infarction

Exercise training has been reported to alleviate cardiac fibrosis and ameliorate heart dysfunction after myocardial infarction (MI), but the molecular mechanism is still not fully clarified. Fibroblast growth factor 21 (FGF21) exerts a protective effect on the infarcted heart. This study investigate...

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Detalles Bibliográficos
Autores principales: Ma, Yixuan, Kuang, Yixin, Bo, Wenyan, Liang, Qiaoqin, Zhu, Wenfei, Cai, Mengxin, Tian, Zhenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623999/
https://www.ncbi.nlm.nih.gov/pubmed/34830222
http://dx.doi.org/10.3390/ijms222212341