Cargando…
Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGF-β1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial Infarction
Exercise training has been reported to alleviate cardiac fibrosis and ameliorate heart dysfunction after myocardial infarction (MI), but the molecular mechanism is still not fully clarified. Fibroblast growth factor 21 (FGF21) exerts a protective effect on the infarcted heart. This study investigate...
Autores principales: | Ma, Yixuan, Kuang, Yixin, Bo, Wenyan, Liang, Qiaoqin, Zhu, Wenfei, Cai, Mengxin, Tian, Zhenjun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623999/ https://www.ncbi.nlm.nih.gov/pubmed/34830222 http://dx.doi.org/10.3390/ijms222212341 |
Ejemplares similares
-
The Roles of FGF21 and ALCAT1 in Aerobic Exercise-Induced Cardioprotection of Postmyocardial Infarction Mice
por: Bo, Wenyan, et al.
Publicado: (2021) -
HIF‐1α‐induced up‐regulation of microRNA‐126 contributes to the effectiveness of exercise training on myocardial angiogenesis in myocardial infarction rats
por: Song, Wei, et al.
Publicado: (2020) -
ADRB2 inhibition combined with antioxidant treatment alleviates lung fibrosis by attenuating TGFβ/SMAD signaling in lung fibroblasts
por: Wan, Ruyan, et al.
Publicado: (2023) -
Dynamic resistance exercise increases skeletal muscle-derived FSTL1 inducing cardiac angiogenesis via DIP2A–Smad2/3 in rats following myocardial infarction
por: Xi, Yue, et al.
Publicado: (2021) -
ACPA Alleviates Bleomycin-Induced Pulmonary Fibrosis by Inhibiting TGF-β-Smad2/3 Signaling-Mediated Lung Fibroblast Activation
por: Chen, Dongxin, et al.
Publicado: (2022)