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In Vitro Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Amphotericin B against Candida auris

The aims of this study were to characterize the antifungal activity of amphotericin B against Candida auris in a static in vitro system and to evaluate different dosing schedules and MIC scenarios by means of semi-mechanistic pharmacokinetic/pharmacodynamic (PK/PD) modelling and simulation. A two-co...

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Detalles Bibliográficos
Autores principales: Caballero, Unai, Eraso, Elena, Pemán, Javier, Quindós, Guillermo, Vozmediano, Valvanera, Schmidt, Stephan, Jauregizar, Nerea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624019/
https://www.ncbi.nlm.nih.gov/pubmed/34834182
http://dx.doi.org/10.3390/pharmaceutics13111767