Compartmental and COMSOL Multiphysics 3D Modeling of Drug Diffusion to the Vitreous Following the Administration of a Sustained-Release Drug Delivery System

The purpose of this study was to examine antibiotic drug transport from a hydrogel drug delivery system (DDS) using a computational model and a 3D model of the eye. Hydrogel DDSs loaded with vancomycin (VAN) were synthesized and release behavior was characterized in vitro. Four different compartment...

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Detalles Bibliográficos
Autores principales: Dosmar, Emily, Vuotto, Gabrielle, Su, Xingqi, Roberts, Emily, Lannoy, Abigail, Bailey, Garet J., Mieler, William F., Kang-Mieler, Jennifer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624029/
https://www.ncbi.nlm.nih.gov/pubmed/34834276
http://dx.doi.org/10.3390/pharmaceutics13111862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624029/
https://www.ncbi.nlm.nih.gov/pubmed/34834276
http://dx.doi.org/10.3390/pharmaceutics13111862

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