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Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Fas(lpr) Mice

KH-type splicing regulatory protein (KSRP) is an RNA-binding protein that promotes mRNA decay and thereby negatively regulates cytokine expression at the post-transcriptional level. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by dysregulated cytokine expression causing...

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Detalles Bibliográficos
Autores principales: Schmidtke, Lisa, Meineck, Myriam, Saurin, Sabrina, Otten, Svenja, Gather, Fabian, Schrick, Katharina, Käfer, Rudolf, Roth, Wilfried, Kleinert, Hartmut, Weinmann-Menke, Julia, Pautz, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624031/
https://www.ncbi.nlm.nih.gov/pubmed/34831390
http://dx.doi.org/10.3390/cells10113167