Understanding the Mechanism of Action of NAI-112, a Lanthipeptide with Potent Antinociceptive Activity

NAI-112, a glycosylated, labionine-containing lanthipeptide with weak antibacterial activity, has demonstrated analgesic activity in relevant mouse models of nociceptive and neuropathic pain. However, the mechanism(s) through which NAI-112 exerts its analgesic and antibacterial activities is not kno...

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Detalles Bibliográficos
Autores principales: Tocchetti, Arianna, Iorio, Marianna, Hamid, Zeeshan, Armirotti, Andrea, Reggiani, Angelo, Donadio, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624038/
https://www.ncbi.nlm.nih.gov/pubmed/34833857
http://dx.doi.org/10.3390/molecules26226764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624038/
https://www.ncbi.nlm.nih.gov/pubmed/34833857
http://dx.doi.org/10.3390/molecules26226764

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