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Understanding the Mechanism of Action of NAI-112, a Lanthipeptide with Potent Antinociceptive Activity
NAI-112, a glycosylated, labionine-containing lanthipeptide with weak antibacterial activity, has demonstrated analgesic activity in relevant mouse models of nociceptive and neuropathic pain. However, the mechanism(s) through which NAI-112 exerts its analgesic and antibacterial activities is not kno...
Autores principales: | Tocchetti, Arianna, Iorio, Marianna, Hamid, Zeeshan, Armirotti, Andrea, Reggiani, Angelo, Donadio, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624038/ https://www.ncbi.nlm.nih.gov/pubmed/34833857 http://dx.doi.org/10.3390/molecules26226764 |
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