Impact of Sodium Dichloroacetate Alone and in Combination Therapies on Lung Tumor Growth and Metastasis

Metabolic reprogramming has been recognized as an essential emerging cancer hallmark. Dichloroacetate (DCA), an inhibitor of pyruvate dehydrogenase kinase (PDK), has been reported to have anti-cancer effects by reversing tumor-associated glycolysis. This study was performed to explore the anti-cance...

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Detalles Bibliográficos
Autores principales: Al-Azawi, Aya, Sulaiman, Shahrazad, Arafat, Kholoud, Yasin, Javed, Nemmar, Abderrahim, Attoub, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624089/
https://www.ncbi.nlm.nih.gov/pubmed/34830434
http://dx.doi.org/10.3390/ijms222212553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624089/
https://www.ncbi.nlm.nih.gov/pubmed/34830434
http://dx.doi.org/10.3390/ijms222212553

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