Discovery and Development of Inhibitors of the Plasmodial FNT-Type Lactate Transporter as Novel Antimalarials

Plasmodium spp. malaria parasites in the blood stage draw energy from anaerobic glycolysis when multiplying in erythrocytes. They tap the ample glucose supply of the infected host using the erythrocyte glucose transporter 1, GLUT1, and a hexose transporter, HT, of the parasite’s plasma membrane. Per...

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Detalles Bibliográficos
Autores principales: Nerlich, Cornelius, Epalle, Nathan H., Seick, Philip, Beitz, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624176/
https://www.ncbi.nlm.nih.gov/pubmed/34832972
http://dx.doi.org/10.3390/ph14111191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624176/
https://www.ncbi.nlm.nih.gov/pubmed/34832972
http://dx.doi.org/10.3390/ph14111191

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