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Interpretation of Single-Molecule Force Experiments on Proteins Using Normal Mode Analysis

Single-molecule force spectroscopy experiments allow protein folding and unfolding to be explored using mechanical force. Probably the most informative technique for interpreting the results of these experiments at the structural level makes use of steered molecular dynamics (MD) simulations, which...

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Detalles Bibliográficos
Autores principales: Bauer, Jacob, Žoldák, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624234/
https://www.ncbi.nlm.nih.gov/pubmed/34835560
http://dx.doi.org/10.3390/nano11112795